Exeter Chiefs backrow Sam Simmonds has received his maiden senior England call-up, while Denny Solomona has been recalled and flanker James Haskell left out of the 34-man squad.
The Sale wing is back in the squad, two months after being ejected from Eddie Jones’ camp for late-night drinking.
Bath flanker Zach Mercer and Harlequins fly-half Marcus Smith have been included as ‘apprentice players’.
Captain Dylan Hartley has been named in the squad after a citing complaint against him dismissed, while Wasps No 8 Nathan Hughes also makes the cut despite a two-week suspension for striking during Sunday afternoon’s Champions Cup win over Harlequins.
Joe Marler and Kyle Sinckler, both currently suspended, have been omitted from the squad.
England will face Argentina, Australia and Samoa throughout November, all live on Sky Sports.
“Our first match against Argentina in the Old Mutual Wealth Series is a significant game for England and everything we have been doing in our training camps so far this season has been geared around getting the detail right in our preparation on how we want to play and win against them next month,” Jones said.
“This will be the fourth time we have played against Argentina in the last 12 months and the last time we play them before 2019, so we want to make sure our record against them is 4-0.”
Backs: Mike Brown (Harlequins), Elliot Daly (Wasps), Jonny May (Leicester Tigers), Denny Solomona (Sale Sharks), Anthony Watson (Bath Rugby), Danny Care (Harlequins), Owen Farrell (Saracens), George Ford (Leicester Tigers), Piers Francis (Northampton Saints), Jonathan Joseph (Bath Rugby), Alex Lozowski (Saracens), Henry Slade (Exeter Chiefs), Marcus Smith (Harlequins) *, Ben Youngs (Leicester Tigers)
Forwards: Tom Curry (Sale Sharks), Charlie Ewels (Bath Rugby), Nathan Hughes (Wasps), Nick Isiekwe (Saracens), Maro Itoje (Saracens), George Kruis (Saracens), Joe Launchbury (Wasps), Courtney Lawes (Northampton Saints), Zach Mercer (Bath Rugby) *, Chris Robshaw (Harlequins), Sam Simmonds (Exeter Chiefs), Sam Underhill (Bath Rugby), Dan Cole (Leicester Tigers), Tom Dunn (Bath Rugby), Ellis Genge (Leicester Tigers), Jamie George (Saracens), Dylan Hartley (Northampton Saints), Matt Mullan (Wasps), Mako Vunipola (Saracens), Harry Williams (Exeter Chiefs)